The elastic post-buckling behavior of thin plates covers a relatively vast region in which geometry nonlinearity (large deflection) and material linearity (Hooke’s low) are realized. In this region, a thin rectangular plate has constant stiffnesses in both orthogonal directions. Few simplified analysis guidelines have been analytically represented for in-plane stiffnesses of an elastic post-buckled thin plate subjected to biaxial loads. In this study, Marguerre’s equations (the generalized form of von Karman equations), which describe the elastic post-buckling behavior of imperfect thin plates, are solved. Galerkin’s method is used to solve these equations in a semi-analytical procedure. Simply supported imperfect thin rectangular plates are considered, and the stresses and displacements functions are obtained in two orthogonal directions to determine corresponding in-plane stiffnesses of the plate. Also, the maximum applicable load is obtained so that the material’s linear behavior is maintained. The semi-analytical procedure has accuracy enough to predict the in-plane stiffness of post-buckled plates and can be easily used for practical purposes.