For improving function of sensors, one can modify their surface with new fullerene-based nanostructure or nanocomposite, especially through hosting. In this work, Fullerene/Lead Iodide (C60/PbI2) recombinant was introduced and its use was investigated as modifier of biosensors. Results show that C60/PbI2 has bandgap-free, p symmetry and paramagnetic properties. Charge carriers were highly mobile specifically for hole. The electron energy loss spectroscopy peak showed the existence of C60/PbI2 on the modified nanobiosensors. High energy radiation did not propagate by orbitals҆ electrons. Electromagnetic radiation with energy value of 1–6 eV was absorbed with less than 20% of reflectivity. The refractive index for C60/PbI2 corresponded to yellow light. Based on results, this structure is good for surface modification of sensors to be used in biomaterial sensing applications.