: Cadmium has been considered as a dangers carcinogen primarily on the basis of its induction of pulmonary tumors. Abnormally high levels of cadmium in the diet also enhance the rates of several cancers in humans. During April 2011, 48 samples of raw whole milk were collected from milk and milk product factories in different regions of the Hamadan province in western Iran and analyzed by Atomic Absorption Spectroscopy. The mean level of cadmium in the all samples were lower than the permissible level of cadmium in samples (mean = 3.21 µg/kg SD =0.81). According to the author`s preperception there were several factors which could affect the residue in raw milk. These factors can be named as the number of automobile, population and number of industrial factories. However there was no statistically significant relationship between these factors and the amount of Cadmium in the samples. The authors found out that under investigation regions which have the highest residue of Cadmium in the samples are located on the areas with the most number of metallic mines.