In this study EDM milling process parameters of AISI H13, have been investigated by using Response Surface Methodology (RSM). Current (16 -32A), pulse-on time (100-700 µs) and depth of cut (1-3mm) were considered as independent variables, while surface roughness, tool wear ratio (TWR), and material removal rate (MRR) as process output responses. Results reveal that increases in the current and decreases in pulse-on time cause more MRR and more TWR and depth of cutting has no significant effect on them. Minimum surface roughness, minimum TWR and maximum MRR were considered as optimization criteria. Verification experiments were carried out in order to analyze the results via software. Optimized settings were used for EDM Milling and die sink EDM experiments to compare the results. The results indicate that using EDM milling has considerable economic savings than die sink EDM, better surface roughness, and higher MRR.