Kelussia odoratissima Mozaff. belonging to the Apiaceae family, is well known for its medicinal and nutritional importance, endemic to Iran. Due to the relatively high time required for the establishment and seed production, it has been announced as an endangered species. Dormancy is a major problem present in Kelussia odoratissima seeds leading to low germination percentage; thus, improvement of seed germination percentage and breaking seed dormancy is important. To evaluate the effects of different treatments on seed germination of Kelussia odoratissima, we designed a set of comparative experiments. This study was done in a completely randomized design with six treatments and three replications. The following treatments were applied: fungal mycelium of Piriformospora indica, spore suspension of P. indica, gibberellic acid, the combination of gibberellic acid and fungal mycelium, the combination of gibberellic acid and spore suspension, and cold treatment. The results showed that gibberellic acid (80.55%) and spore suspension of P. indica (75%) were the most effective treatments for improvement of seed germination and germination velocity. The least coefficient of uniformity of germination (CUG) was seen in spore suspension of P. indica treatment. Among the treatments, spore suspension of P. indica treatment had the maximum index for the times for 10% germination (D 10 ) and 90% germination (D ). Based on the current results, it seems that gibberellic acid and spore suspension of P. indica was more successful than cold treatment as a common method in breaking dormancy. The results will help to reduce germination time and domestication of medicinal herb Kelussia odoratissima Mozaff.