The additive effects of aflatoxin (AF) and T-2 toxin (T-2) on the performance of broiler chickens were evaluated, individually and in combination. One hundred and sixty eight day-old Cobb broiler chicks were obtained from a commercial hatchery and divided into four groups in 2X2 Complete Randomized Design of three replicates and fourteen chicks per replicate, with dietary treatments of 0.0 (control), 0.5μg/g AF, 2.0μg/g T-2 and their combination (0.5 μg/g AF+2.0 μg/g T-2). The chicks were housed in deep litter independent conventional system with feed and water ad libitum throughout the experimental study. The toxin fed chicks have exhibited a significant (P#0.05) decrease in body weight and feed consumption. The relative weights of pancreas, thymus and bursa of Fabricius were also decreased significantly (P#0.05). These findings were more pronounced in the combined group of AF and T-2. The data from the current study revealed that the presence of AF and T-2 in the diet can produce a synergistic affect on the performance parameters of the chicks.