We have used Fe3O4 as a promising support for heterogenization of 3,4-dihydroxypyridine to make a new magnetically recoverable heterogeneous catalyst.Our experimental results reveal that pyridine-functionalized Fe3O4 nano particles is an efficient base catalyst for the domino condensation of different aromatic aldehydes, Meldrum's acid and 5-methylpyrazol-3-amine under very mild reaction condition and in the presence of ethanol solvent. All reactions were completed in short times and all products were obtained in good to excellent yields. Also notably, the catalyst was reused for five times without significant degradation in catalytic activity and performance