Objective: One of the problems in sports community is the use of energetic drugs by athletes. The purpose of present study was examining the prevalence of energetic drugs use and the role of perfectionism, sensation seeking and physical self-concept in discriminating bodybuilders with positive and negative attitude toward doping. Methodology: This study was a cross- sectional survey. A number of 389 bodybuilders in Kermanshah were selected by clustered sampling; they were asked to complete the scales of attitude toward doping and physical self-concept, sensation seeking, perfectionism, and performance enhancement. Descriptive statistics, Pearson correlation and discriminant analysis were used for analyzing the data. Results: The results showed 32.1% of body builders had used energetic drugs. There was significant relationship between perfectionism (r=0.302), sensation seeking (r=0.31), physical self-concept (r=-0.422) and attitude toward doping. According to the results of discriminant analysis, perfectionism, sensation seeking and physical self-concept significantly discriminated bodybuilders with positive and negative attitude toward doping; the role of this variables in discriminating two groups was 0.335, 0.362, and - 0.406, respectively. Conclusions: The results of this study confirmed the previous researches’ findings and the role of perfectionism, sensation seeking and physical self-concept in discriminating bodybuilders with positive and negative attitude toward doping.