Today, overtaking different antibiotics transformed organisms into resistant phase, which few antibiotics can effect on them. Geranium oil contains citronellal (31.7%), citronellal format (12.8%), and geraniol (9.8%) as major components. Geraniol plays effective role in antibacterial effect of geranium oil. The aim of present study was to evaluate the effect of geranium oil on bacteria and a new component for antibiotics. In this study the effect of Geranium oil was evaluated on E. coli, Bacillus, Pseudomonas aeruginosa and Staphylococcus aureus. For antibacterial effect evaluation, bacteria were cultured in nutrient broth media overnight and then cultured in nutrient agar media and effect of Geranium oil evaluated by well diffusion method and the inhibition region diameter were measured. The inhibition diameter for E. coli was 12mm, the inhibition diameter for Bacillus was 25mm, the inhibition diameter for Staphylococcus aureus was 15mm and inhibition diameter for Pseudomonas aeruginosa was 0 mm. Based on these results, Geranium oil can be used as new component for antibiotics to have better effects on bacteria and therefore can have good effect on resistance of bacteria and can be used in recombinant drugs instead of new chemical and harmful new components.
