Unlike previous feminist critics who sought to reduce the otherness of the women in order to help them be the same as subject, the man, Luce Irigaray strongly emphasizes the irreducibility of the women's place as the "Other". Concerned with the concept of sexual difference and the otherness of women, Irigaray occupies a unique place among feminist critics. Irigaray's aim is not to be the "same," but to make a clear border between these two sexually different creatures. Undoubtedly, this is one of those crucial issues which Sandra Cisneros covers intelligently in her novels. The "place" of the "Other," occupied unfairly by the empowered men, is clearly understandable by rereading Sandra Cisneros's novel, The House on Mango Street (1984) in the light of Irigaray’s sexual difference. Based on sexual difference, both men and women should stand in their bordered place and they cannot be substituted for the other and unlike other feminist studies which emphasize sameness of men and women, this study tries to show them as unique and different entities. By writing this novel and using female characters who struggle to regain their place occupied by men in most cases, Sandra Cisneros, aims at taking separate subject position for women.