Objectives:Inthis study, the effect of adding fenugreek (Trigonellafoenum L.) and Savory (Saturejahortensis L.) powder, individually or in combination, on humoral immunity response in White Leghorn layer (Hy-line W36.) was investigated. Materials & Methods: The experimental design was completely randomized, repeated mesurement analysis including: Group1: receiving the basal diet (without addition of any medicinal plants), Group2: receiving the basal diet with 1% fenugreek powder, three: receiving the basal diet with 1% Savory powder, fourth experimental group: basal diet with Fenugreek powder and Savory powder at 0.5 percent. This study was designed for and carried out on 128 white leghorn layer (Hy-line W36) at the age of 75 weeks and after molting, with 4 treatments, 8 replicates and 4 observations per replicates, after 2 weeks’ primary adjustment, in three periods (total period of treatment 63 days). Humoral immunity was assayed 3 times for ND, AI antibody in serum by HI analysis. Results & Conclusion: The results in the experimental groups showed no significant effect on antibody titiers against influenza and Newcastle disease. Keywords: biochemical, Egg, Fenugreek, Savory, Layer, Iran.
