08 خرداد 1403
محمود ناصري

محمود ناصری

مرتبه علمی: دانشیار
نشانی:
تحصیلات: دکترای تخصصی / فیزیک-نانو
تلفن: 08132355404
دانشکده: دانشکده علوم پایه

مشخصات پژوهش

عنوان
The study of the effect of calcination temperature of CaFe2O4@PVA nanocarriers on HEK-293 cells activity
نوع پژوهش مقاله ارائه شده
کلیدواژه‌ها
Calcium, Curcumin, Magnetite, PVA, Drug delivery
سال
2021
پژوهشگران محمود ناصری

چکیده

In this study, calcium ferrite/polyvinyl alcohol (CaFe2O4@PVA) nanocarriers were prepared by a thermal-treatment method at three different temperatures (773, 823, and 923 K). The nanocarriers were used as drug delivery systems (DDS) to deliver Curcumin (CUR). Drug loading and release study of CUR was performed and it was observed that nanocarriers showed a pH-dependent drug release behavior. The cell viability of Ca 823, was more than 70%, this result revealed that Ca 823 had very low adverse effect and toxicity on healthy cells. Therefore, it was revealed that this nanocarrier is suitable to be utilized as drug delivery systems.