1404/04/22
محمود ناصری

محمود ناصری

مرتبه علمی: استاد
ارکید:
تحصیلات: دکترای تخصصی
اسکاپوس:
دانشکده: دانشکده علوم پایه
نشانی:
تلفن: 08132355404

مشخصات پژوهش

عنوان
بررسی تاثیر دمای کلسیناسیون نانوحامل های CaFe2O4@PVA بر فعالیت سلول های HEK-293
نوع پژوهش
Presentation
کلیدواژه‌ها
Calcium, Curcumin, Magnetite, PVA, Drug delivery
سال
2021
پژوهشگران mahmoud naseri

چکیده

In this study, calcium ferrite/polyvinyl alcohol (CaFe2O4@PVA) nanocarriers were prepared by a thermal-treatment method at three different temperatures (773, 823, and 923 K). The nanocarriers were used as drug delivery systems (DDS) to deliver Curcumin (CUR). Drug loading and release study of CUR was performed and it was observed that nanocarriers showed a pH-dependent drug release behavior. The cell viability of Ca 823, was more than 70%, this result revealed that Ca 823 had very low adverse effect and toxicity on healthy cells. Therefore, it was revealed that this nanocarrier is suitable to be utilized as drug delivery systems.