Resveratrol (3, 4’, 5-trihydroxystilbene) and Pterostilben (3',5'-Dimethoxy-4-stilbenol) are present in family of Vitaceae plants that are producing in biological and non-biological stresses. In this research, amount of anti-cancer compound were investigated in 26 grape cultivars. Studies showed that "resveratrol" can be extract in some parts of grape such as; stems, roots, petioles and lateral buds. Between different organs of grape, stem phloem and leaves have maximum and minimum content of "resveratrol" respectively. Also, berry skin has high amounts of "resveratrol", while this compound does not exist in mesocarp. Red grapes, due to greater accumulation of antioxidant (anthocyanins), have high amounts of "trans-resveratrol". "Resveratrol" is phenolic compound which has powerful antioxidant and anti-inflammatory properties. This compound can be accumulated in different parts of grape in response to biological and non-biological stresses such as; fungi diseases, ultraviolet radiation and chemical materials. Research shows that "resveratrol" is effective to prevent the growth of human cancer cells including; breast, prostate, stomach, colon, pancreas and thyroid cancers. The "resveratrol" can delay aging by activating the longevity gene (SIRT1).
