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چکیده
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This study investigated the synergistic effects of incorporating collagen type I into hydroxyapatite (HA) coatings on anodized Ti-6Al-4V substrates to enhance their biocompatibility and performance for biomedical applications. HA coatings were electrochemically deposited onto anodized Ti-6Al-4V, and collagen was subsequently incorporated via a soaking method. The coatings were characterized using GI-XRD, FESEM, AFM, nanoindentation, nanoscratch testing, and EIS. GI-XRD confirmed the presence of both anatase and rutile TiO2 in the anodized layer and revealed that collagen influenced HA crystallization, promoting the formation of aligned, elongated HA crystals. FESEM and AFM analyses showed a 30% reduction in surface roughness upon collagen incorporation, attributed to collagen filling HA pores. Nanoindentation testing demonstrated a decrease in Young's modulus from 0.2 GPa for HA to 0.1 GPa for the HA-collagen composite, and hardness decreased from 0.07 GPa to 0.01 GPa, respectively. Nanoscratch testing revealed improved wear resistance for the HA-collagen composite, with the coefficient of friction decreasing from 1.12 to 0.94 during scratching. EIS studies showed a two-fold increase in charge transfer resistance for the HA-collagen coating, indicating enhanced corrosion protection. These results suggest that the HA-collagen composite coating offers a promising approach for improving the long-term performance and clinical success of biomedical implants by enhancing cell adhesion, mitigating stress shielding, improving wear resistance, and enhancing corrosion protection.
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